ea0056p308 | Cardiovascular Endocrinology and Lipid Metabolism | ECE2018
Francic Vito
, Gaksch Martin
, Schwetz Verena
, Trummer Christian
, Pandis Marlene
, Aberer Felix
, Grubler Martin
, Verheyen Nicolas D
, Marz Winfried
, Pieber Thomas R
, Tomaschitz Andreas
, Pilz Stefan
, Obermayer-Pietsch Barbara
Introduction: Soluble ST2 (sST2) is the truncated soluble form of the ST2 receptor in the circulation. It is a decoy receptor of IL-33 and thereby inhibits the effects of IL-33/ST2 signaling. Elevated levels of sST2 have been associated with various adverse cardiovascular outcomes. Recently, potential associations of sST2 with obesity and type 2 diabetes mellitus (T2DM) have been described in the general population. In this study, we determined possible cross-sectional associa...